Overview
Cholesterol Reduction in Seniors Program (CRISP)
Status:
Completed
Completed
Trial end date:
1992-06-01
1992-06-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
To conduct a pilot study to determine whether lowering elevated serum cholesterol levels with 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG CoA) reductase inhibitors reduced mortality due to the sequelae of atherosclerotic cardiovascular disease in older men and women.Phase:
Phase 2Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
National Heart, Lung, and Blood Institute (NHLBI)Treatments:
Dihydromevinolin
L 647318
Lovastatin
Criteria
Men and women, ages 65 and older, with elevated low-density lipoprotein cholesterol levelsbetween 159 and 221 mg/dl at entry.