Chlorthalidone and HCTZ Impacts on Platelet Activation
Status:
Unknown status
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
This will be a randomized, double-blinded, three-period crossover study of platelet
activation and aggregation in 30 non-smoking healthy volunteers comparing chlorthalidone
(CTD), hydrochlorothiazide (HCTZ), and aspirin (ASA; active control). The study hypothesis is
that CTD has different effects on platelet activation and aggregation than HCTZ.