Overview

Chlorproguanil/Dapsone Compared With Chloroquine and SP for Vivax Malaria

Status:
Completed
Trial end date:
2006-03-01
Target enrollment:
Participant gender:
Summary
To determine whether two cheap antifolates (chlorproguanil-dapsone and sulfadoxine-pyrimethamine) which work against falciparum malaria in this region are sufficiently effective against vivax malaria to be deployed in areas where diagnosis is poor and the burden of malaria is high, a randomised controlled trial of the three drugs is being undertaken comparing their efficacy in treating malaria.
Phase:
Phase 3
Details
Lead Sponsor:
Gates Malaria Partnership
London School of Hygiene and Tropical Medicine
Collaborator:
HealthNet TPO
Treatments:
Chloroquine
Chloroquine diphosphate
Chlorproguanil
Dapsone
Fanasil, pyrimethamine drug combination
Proguanil
Pyrimethamine
Sulfadoxine