Chlorpheniramine Maleate Nasal Spray for Chronic Rhinitis
Status:
Active, not recruiting
Trial end date:
2021-12-30
Target enrollment:
Participant gender:
Summary
Allergic rhinitis is defined as the symptoms of sneezing, nasal itching, airflow obstruction,
and, mostly, clear nasal discharge caused by IgE-mediated reactions against inhaled allergens
and involving mucosal inflammation driven by T cells (Th2) auxiliary type 2. pollens and
molds, as well as allergens from perennial interiors, such as dust mites, pets, pests, and
some molds. The pattern of dominant allergens depends on the geographic region and degree of
urbanization, but the general prevalence of sensitization to allergens does not vary among
census districts in the United States. This research proposes to study a separate
antihistamine in a nasal spray. It is important to note that this antihistamine is available
without prescription (OTC) and has been studied intranasal since the 1950s1