Chloroquine and Coartem for Treatment of Symptomatic Children With Plasmodium Falciparum in Guinea Bissau
Status:
Completed
Trial end date:
2008-11-01
Target enrollment:
Participant gender:
Summary
This study will evaluate the efficacy of treatment with artemether-lumefantrine as compared
to chloroquine in the dose of 50 mg/kg for treatment of malaria in children in Guinea-Bissau.
The genetic basis of the parasites for developing resistance will be examined. Children
coming to one of the Health Centres with symptoms of malaria and a positive malaria test will
be included. The children will be followed weekly until day 70. In case of reappearance of
parasites the child will be re-treated with the opposite study drug.