Chloroquine and Amodiaquine for Treatment of Malaria in Children
Status:
Completed
Trial end date:
2004-05-01
Target enrollment:
Participant gender:
Summary
This study will evaluate the efficacy of the treatment recommended by the National Malaria
Programme in Guinea-Bissau as compared to a higher dose of chloroquine and to another
anti-malarial drug, amodiaquine. The genetic basis of the parasites for developing resistance
will be examined. Children coming to Bandim Health Centre with symptoms of malaria and a
positive malaria test will be included. The children will be visited and malaria films will
be obtained weekly until day 35. In case of a reappearance of parasites the children will be
re-treated with sulfadoxine/pyrimethamine.