Chloroprocaine Spinal Anesthesia for Cervical Cerclage (CP Spinal)

• Status: Completed
• Trial end date: 2020-01-31
• Target enrollment: 0
• Participant gender: Female

Summary

This study aims to determine whether or not spinal anesthesia with the local anesthetic drug, chloroprocaine, wears off faster than the local anesthetic drug, bupivacaine, and results in faster discharge from the post-anesthesia care unit after surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Columbia University
• Treatments: Anesthetics; Bupivacaine; Chloroprocaine; Fentanyl; Procaine

Criteria

Inclusion Criteria:

• ASA I and II women

• 18-45 yrs old

• Singleton pregnancy

• Cervical cerclage 1st or 2nd trimester of pregnancy undergoing with spinal anesthesia

• Height 150 - 180 cm

• BMI ≤ 40 kg/m2.

Exclusion Criteria:

• Any contraindication to neuraxial anesthesia (history of neurologic disease (e.g., multiple sclerosis, spinal stenosis, central or peripheral neuropathy)

• Pre-existing/chronic back pain

• Ester local anesthetic allergy, PABA allergy

• History of atypical cholinesterase (CP is metabolized by cholinesterase)