Chlorhexidine vs Povidone Iodine in Alcoholic Solutions for Prevention of Central Venous Catheter Infection
Status:
Completed
Trial end date:
2006-04-01
Target enrollment:
Participant gender:
Summary
The best antiseptic solution for cateheter care remains unknown.High concentration in aquous
solution or low concentration in alcoholic solution of chlorhexidine actbetter than povidone
iodine in aquous solutions. No study has compare alcoholic formulations of low concentration
of chlorhexidine and povidone iodine for skin disinfection prior to insertion of central
venous catheters.
To compare the incidence of central venous catheter colonization after skin disinfection with
either an alcoholic solution of povidone iodine or a combination of 0.5% chlorhexidine,
0.025% Benzalkonium and 4% benzylic alcohol.
To compare the incidence of catheter related bacteremia in the to study groups. To compare
the local and general tolerance of the two antiseptic formulations