Chlorhexidine & Pneumonia in Nursing Home Residents

• Status: Completed
• Trial end date: 2011-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is determine if topical oral application of a chlorhexidine antimicrobial spray will significantly reduce pneumonia and respiratory infections, and improve oral health compared to a placebo solution in nursing home residents.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Louisville
• Collaborator: National Institute of Dental and Craniofacial Research (NIDCR)
• Treatments: Chlorhexidine; Chlorhexidine gluconate

Criteria

Inclusion Criteria:

1. Participants must be at least 65 years old.

2. Be dependent in 2 or more Activities of Daily Living as noted on the nursing home resident's Minimum Data Set - One must be ADL J- Personal Hygiene.

3. Have natural teeth and/or wear complete or partial dentures.

4. Expected to be a resident in a nursing home for two years.

Exclusion Criteria:

1. Existing pneumonia.

2. History of chlorhexidine reaction or allergy and/or multiple medication or substance allergies.

3. Receiving chlorhexidine oral application at enrollment as prescribed by physician or dentist.