Chlorhexidine Vaginal Preparation for Reduction of Post-cesarean Endometritis and Sepsis

• Status: Recruiting
• Trial end date: 2021-08-30
• Target enrollment: 0
• Participant gender: Female

Summary

The study aims to assess the beneficial value of vaginal preparation with chlorhexidine gluconate 0.05% before cesarean delivery of cases in labor in reduction of postoperative endometritis, fever and wound complications compared to no preparation or using saline only.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Zagazig University
• Treatments: Chlorhexidine; Chlorhexidine gluconate

Criteria

Inclusion Criteria:

1. Gestational age ≥28 weeks.

2. Cases had cesarean section after start of labor.

Exclusion Criteria:

1. Women with known allergy to chlorhexidine gluconate or any of its ingredients.

2. Women with diagnosed group B streptococcus (GBS) colonization.

3. Women with active infection during the procedure.

4. Women did not receive the standard preoperative antibiotic prophylaxis.

5. Women with diagnosis of chorioamnionitis.

6. Prolonged rupture of membranes >7 days