Overview

Chlorhexidine Mouthwash and Oral Nitrate in Adults With Pulmonary Hypertension

Status:
Not yet recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
This is an open-label, single-center study to examine distinguishing features of the structure and function of the oral and gut microbiome in volunteers with PH in the breakdown of oral nitrate and effect on hemodynamics.
Phase:
Phase 1
Details
Lead Sponsor:
Gladwin, Mark, MD
Collaborators:
National Heart, Lung, and Blood Institute (NHLBI)
National Institutes of Health (NIH)
University of Pittsburgh
Treatments:
Chlorhexidine
Chlorhexidine gluconate