Chlorhexidine Gluconate Versus Povidone-Iodine as Vaginal Preparation Antiseptics Prior to Cesarean Delivery

• Status: Completed
• Trial end date: 2017-12-30
• Target enrollment: 0
• Participant gender: Female

Summary

Primary Hypothesis: chlorhexidine gluconate antiseptic vaginal preparation is superior to povidone-iodine vaginal preparation in decreasing the bacterial load within the vagina when prepping prior to a cesarean section.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Metro Health, Michigan
• Treatments: Anti-Infective Agents, Local; Cadexomer iodine; Chlorhexidine; Chlorhexidine gluconate; Iodine; Povidone; Povidone-Iodine

Criteria

Inclusion Criteria:

• Scheduled low transverse cesarean section (can be primary or repeat)

• Term gestation ≥ 37 weeks

Exclusion Criteria:

• Allergy to either antiseptic

• Rupture of amniotic membranes

• Preterm gestation

• Active labor

• Emergency or unscheduled cesarean sections

• Infection diagnosis on admission

• Vaginal infection or any treatment of vulvovaginitis in prior 7 days

• Patients under the age of 18 years