Overview

China Post-approval Commitment (PAC) Study of Avalglucosidase Alfa in Participants With IOPD

Status:
RECRUITING
Trial end date:
2028-05-02
Target enrollment:
Participant gender:
Summary
This is a single group, 52-week treatment, Phase 4, open-label, single-arm study to assess the safety and efficacy of avalglucosidase alfa IV infusion in male and female Chinese participants with IOPD who are treatment-nave or were previously treated with ERT. Study details include: * The study duration: total study duration is approximately 64 weeks. * Screening period of up to 8 weeks * Treatment period of 52 weeks * Follow-up period of 4 weeks. * The number of visits will be 30, including 29 site visits and 1 phone call follow-up visit.
Phase:
PHASE4
Details
Lead Sponsor:
Genzyme, a Sanofi Company
Treatments:
GAA protein, human