Overview

Chidamide With R-CHOP Regimen for DLBCL Patients

Status:
Unknown status
Trial end date:
2020-02-05
Target enrollment:
Participant gender:
Summary
It's a prospective, single arm, open label phase II clinical trial, in which the safety and efficacy of Chidamide plus R-CHOP regimen is accessed in de novo DLBCL patients, who have received 2 courses of R-CHOP but only achieved PR or whose MRD tests for ctDNA revealed positive results. abbreviation: R-CHOP: the chemo-therapy regimen composed of Rituximab, cyclophosphoamide, etoposide, vincristine and prednisone. PR: partial remission; MRD:minimal residual disease;
Phase:
Phase 2
Details
Lead Sponsor:
First Affiliated Hospital of Zhejiang University
Treatments:
Cyclophosphamide
Doxorubicin
Prednisolone
Prednisone
Rituximab
Vincristine