Chest Pain Perception and Capsaicin Sensitivity in Patients With Acute Cardiac Ischemia

• Status: Completed
• Trial end date: 2015-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether there is a positive correlation between the ability to sense chest pain in the context of myocardial ischemia and the ability to sense discomfort associated with the topical application of the TRPV1 agonist capsaicin (the active ingredient on hot chili peppers).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bassett Healthcare
• Treatments: Capsaicin

Criteria

Inclusion Criteria:

Subjects will consist of patients who have undergone clinically-indicated PCI for the treatment of coronary artery disease. This study will include clinically unstable patients, such as those undergoing emergency percutaneous coronary intervention (PCI) for acute myocardial infarction, etc.

Exclusion Criteria:

Patients with documented hypersensitivity to capsaicin will be excluded and patients who have used a capsaicin-based product within the last 3 months will be excluded