Overview

Chemotherapy and Peripheral Stem Cell Transplantation Followed By Immunotherapy in Treating Patients With Multiple Myeloma

Status:
Completed
Trial end date:
2008-02-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with autologous peripheral stem cell transplantation and immunotherapy may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. PURPOSE: Randomized phase I/II trial to study the effectiveness of combining chemotherapy with peripheral stem cell transplantation followed by immunotherapy in treating patients who have multiple myeloma.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
University of Maryland
University of Maryland, Baltimore
Collaborator:
University of Maryland Greenebaum Cancer Center
Treatments:
Carmustine
Cyclophosphamide
Heptavalent Pneumococcal Conjugate Vaccine
Melphalan
Vaccines