Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer
Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Combining more than one drug or combining radiation therapy with
chemotherapy may kill more tumor cells. It is not yet known whether fluorouracil and
mitomycin plus radiation therapy is more effective than fluorouracil and cisplatin plus
radiation therapy for anal cancer.
PURPOSE: This randomized phase III trial is studying fluorouracil and mitomycin plus
radiation therapy to see how well it works compared to fluorouracil and cisplatin plus
radiation therapy in treating patients with stage II or stage III anal cancer.
Phase:
Phase 3
Details
Lead Sponsor:
Radiation Therapy Oncology Group
Collaborators:
Cancer and Leukemia Group B Eastern Cooperative Oncology Group National Cancer Institute (NCI) North Central Cancer Treatment Group Southwest Oncology Group