Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Disease
Status:
Completed
Trial end date:
2008-06-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing
so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer
cells. Combining chemotherapy with radiation therapy may kill more cancer cells. It is not
yet known if chemotherapy is more effective with or without dexrazoxane for Hodgkin's
disease.
PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy,
with or without dexrazoxane, followed by radiation therapy in treating young patients with
newly diagnosed stage I, stage II, or stage III Hodgkin's disease.
Phase:
Phase 3
Details
Lead Sponsor:
Children's Oncology Group
Collaborators:
Children's Cancer Group National Cancer Institute (NCI)