Chemotherapy Combined With Gene Therapy in Treating Patients Who Have Stage III or Stage IV Breast Cancer
Status:
Completed
Trial end date:
2004-08-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Inserting the p53 gene into the tumor may increase the
effectiveness of a chemotherapy drug by making tumor cells more sensitive to the drug.
Combining chemotherapy with gene therapy may kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of combining chemotherapy with gene
therapy in treating patients who have stage III or stage IV breast cancer.