Chemoradiotherapy in Patients With Localised Lung Cancer
Status:
Completed
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
The study compares 2 different methods of combined chemotherapy and radiotherapy for the
treatment of localised lung cancer in patients not suitable for surgery.
Hypothesis(es) to be tested:
1. Vinorelbine + cisplatin + high-dose palliative radiotherapy is superior to gemcitabine +
high dose palliative radiotherapy in terms of efficacy in a multi-institutional setting
2. Vinorelbine + cisplatin + high-dose palliative radiotherapy is superior to gemcitabine +
high dose palliative radiotherapy in terms of feasibility in a multi-institutional
setting
3. Vinorelbine + cisplatin + high-dose palliative radiotherapy has a favourable toxicity
profile relative to gemcitabine + high-dose palliative radiotherapy
Phase:
Phase 2
Details
Lead Sponsor:
Trans Tasman Radiation Oncology Group Trans-Tasman Radiation Oncology Group (TROG)
Collaborators:
Cancer Council Queensland Victorian Cancer Council