Overview

Chemo-free BRCA-targeted Neoadjuvant Strategy

Status:
Not yet recruiting
Trial end date:
2030-02-18
Target enrollment:
Participant gender:
Summary
This is a multicenter randomized phase ll clinical trial to evaluate the pathological complete response (pCR) in the tumour burden (primary and lymph nodes) with olaparib alone or in the olaparib and durvalumab arm in TNBC patients candidate for neoadjuvant strategy showing a t/gBRCAmut or BRCAness/HRD profile.
Phase:
Phase 2
Details
Lead Sponsor:
European Organisation for Research and Treatment of Cancer - EORTC
Collaborator:
AstraZeneca
Treatments:
Durvalumab
Olaparib