Overview

Characterizing Inflammatory Bowel Disease With 68Ga-FAPI PET/CT

Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
0
Participant gender:
All
Summary
68Ga-FAPI has been developed as a tumor-targeting agent as fibroblast activation protein is overexpressed in cancer-associated fibroblasts and some inflammation,such as inflammatory bowel disease. And it might be more sensitive than FDG in detecting a certain type of inflammations according to our preliminary research. Thus this prospective study is going to investigate whether 68Ga-FAPI PET/CT may be superior for diagnosis, therapy response assessment and follow-up of inflammatory bowel disease than 18F-FDG PET/CT.
Phase:
Early Phase 1
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Peking Union Medical College Hospital
Criteria
Inclusion Criteria:

- suspected or confirmed untreated inflammatory bowel disease patients;

- 18F-FDG PET/CT within two weeks;

- signed written consent.

Exclusion Criteria:

- pregnancy;

- breastfeeding;

- known allergy against FAPI

- any medical condition that in the opinion of the investigator may significantly
interfere with study compliance.