Characteristics of Islet β-cell Functions in Chinese Patients With Graves' Disease
Status:
Completed
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
Patients with GD often present with glucose dysregulation, which, according to most studies,
is associated with islet β-cell dysfunctions, enhanced gluconeogenesis and insulin resistance
(IR). Current studies focus mainly on IR, and a few that investigate islet β-cell functions
show inconsistent results. This study examined the characteristics of glucose dysregulation
in Chinese patients with GD, and furthermore evaluated the effects of thyroid dysfunction on
islet β-cell functions and subsequently the carbohydrate metabolism.