Changes of Skin Resistance After Midazolam and After the End of Anaesthesia

• Status: Completed
• Trial end date: 2015-06-26
• Target enrollment: 0
• Participant gender: All

Summary

It has been described that sympathetic activity, measured as changes in electrical skin resistance (SR), may be used to assess the adequacy of general anaesthesia. Our prospective study investigated how far measurements of skin resistance can help determine level of sedation. The secondary aim was to investigate if changes in skin resistance can be used for assessing recovery from anaesthesia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Charles University, Czech Republic
• Treatments: Anesthetics; Midazolam

Criteria

Inclusion Criteria:

• adult patients scheduled for knee arthroscopy or minor plastic surgery under general anaesthesia

Exclusion Criteria:

• previous history of taking drugs affecting mental functions, history of psychic illness, implanted electrical device, know allergy to benzodiazepines, myasthenia gravis, ASA classification ASA 3 and more. All patients consented not to use any medication for sedation or anxiety, opioid analgesics, ethanol and illicit drugs 24 hours before surgery.