Changes in Measured Plasma Volume, Glycocalyx and Atrial Natriuretic Peptide During Anaesthesia
Status:
Completed
Trial end date:
2019-08-20
Target enrollment:
Participant gender:
Summary
The arterial blood pressure is thought to affect the ratio between filtration and
reabsorption of fluids in the circulating blood volume and thereby the plasma volume. During
induction of anesthesia blood pressure, hemoglobin level and hematocrits decreases and the
plasma volume increases. The aim of the study is to evaluate weather a maintained blood
pressure with norepinephrine during anesthesia induction reduces the increase in 125
iodine-labeled human serum albumine (125I-HSA) measured plasma volume.