Changes in Esophageal Distensibility With Proton Pump Inhibitors in Patients With Esophageal Eosinophilia: A Pilot Study
Status:
Recruiting
Trial end date:
0000-00-00
Target enrollment:
Participant gender:
Summary
This pilot study will explore whether treatment of eosinophilic inflammation in the esophagus
is associated with an improved distensibility of the esophagus. Furthermore, previous studies
of the esophagus using EndoFlip only measured distensibility of the distal esophagus,
specifically the distal esophagus and esophagogastric junction. Eosinophilia in EoE has been
demonstrated to affect both upper, middle and lower esophagus. The aim is to measure
distensibility both proximal and distal, before and after treatment.