Changes in Cardiovascular Hemodynamics During Peritoneal Dialysis
Status:
Terminated
Trial end date:
2010-01-01
Target enrollment:
Participant gender:
Summary
During peritoneal dialysis, water is removed from the body. This sometimes occurs at rates of
up to 500 ml/h. During shifts with dialysate with high glucose content, an increase in blood
pressure has been described. The effect upon central hemodynamics is unknown. The researchers
are investigating the effects of low and high glucose dialysate and icodextrin on cardiac
output, stroke volume, pulse rate and blood pressure. The researchers have hypothesized that
the effects seen are induced by vasopressin.