Change of Gut Microbiome and Symptom After H.Pylori Eradication Therapy in Patients With Functional Dyspepsia

• Status: Not yet recruiting
• Trial end date: 2021-10-30
• Target enrollment: 0
• Participant gender: All

Summary

The aims of the investigators' study are to investigate the effect of H.pylori eradication on the human gut microbiome and symptoms of functional dyspepsia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Asan Medical Center
• Treatments: Amoxicillin; Clarithromycin

Criteria

Inclusion Criteria:

• Patients who has diagnosed with functional dyspesia by Rome IV criteria

Exclusion Criteria:

• Known GI malignancy

• Previous Helicobater pylori eradication history

• Severe systemic disease

• Previous GI surgery

• Uncorrectable coagulopathy: INR > 1.5 or platelet < 50,000/ml

• Pregnant or breastfeeding women

• Atrophic gastritis, open type