In ophthalmic surgery, surgical operations such as pulling certain eye tissues or compressing
the eyeball often leads to bradycardia, arrhythmia even cardiac arrest, bradypnea, nausea and
vomiting and elevated blood sugar level. The condition is called the ocularvagal reflex
(OVR). Traditionally, when the bradycardia or arrhythmia happens, the operation has to be
suspended, and atropine or isoproterenol is given intravenously to treat the bradycardia.
Vagus nerve block may be an effective way to prevent and alleviate this vagal reflex. However
it is difficult to perform the nerve block with anatomical landmark (blind) methods. In this
study, the investigators used ultrasound-guided right cervical vagus nerve block to reduce
the incidence of the OVR. The researchers hypothesized that low concentrations of lidocaine
can block the right cervical vagus nerve and reduce the incidence of intraoperative OVR.
Researchers evaluated the changes of heart rate, blood pressure, oxygen saturation, and
airway pressure in patients undergoing high-risk OVR surgery.
Phase:
N/A
Details
Lead Sponsor:
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University