Cervical Rippening With Antiprogesterone in Midtrimester Abortions
Status:
Completed
Trial end date:
2008-05-01
Target enrollment:
Participant gender:
Summary
Induction of midtrimester abortion includes cervical ripening and then contraction to induce
uterine evacuation. There are several protocols, but most of them include using
prostaglandins (PG). The disadvantages of using PG include uncomfortable side effects and
limits of using it for women after cesarean section. Mifepristone is an antiprogesterone drug
and been used for induction of abortion in first and second trimesters abortions. The aim of
this study is to explore the effectiveness of Mifepristone for cervical ripening before high
dose Oxytocin drip.