Cervical Ripening for Induction of Labor: Misoprostol Versus Oxytocin in Conjunction With Foley Balloon

• Status: Completed
• Trial end date: 2010-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to specifically investigate the efficacy of an alternative pharmacologic cervical ripening agent, misoprostol, versus the standard oxytocin, as an adjunct to Foley balloon for induction of the unfavorable cervix.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Aultman Health Foundation
• Treatments: Misoprostol; Oxytocin

Criteria

Inclusion Criteria:

• Participant or surrogate is capable of giving informed consent

• Anticipated number - 50 patients with 25 in each study arm Female with singleton gestation, live intrauterine pregnancy

• Participant is undergoing an indicated induction of labor

• Participant is found to have cervical Bishop score ≤5 on initial cervical exam

• Participant has no medical or obstetrical contraindications to induction of labor

Exclusion Criteria:

• Participant has ≥2 painful contractions in 10 min in 2 subsequent 10 min periods

• Manufacturer's contraindications to misoprostol or oxytocin