Overview

Cervical Ripening With Misoprostol vs Isosorbide Mononitrate ; A Parallel -Arm Randomized Controlled Trial

Status:
ACTIVE_NOT_RECRUITING
Trial end date:
2026-08-31
Target enrollment:
Participant gender:
Summary
This randomized controlled trial compared misoprostol and isosorbide mononitrate (IMN) for cervical ripening in prolonged pregnancies. Low-risk women at 41+6 weeks gestation with an unfavorable cervix were randomized to receive either misoprostol or IMN. The primary outcome was the achievement of cervical ripeness (Bishop Score 6) within 40 hours.
Phase:
NA
Details
Lead Sponsor:
Raid M. Al-Ani
Treatments:
isosorbide-5-mononitrate
Misoprostol
Nitric Oxide Donors