Cervical Pessary vs. Vaginal Progesterone for Preventing Premature Birth in IVF Twin Pregnancies

• Status: Completed
• Trial end date: 2017-11-02
• Target enrollment: 0
• Participant gender: Female

Summary

To compare the effectiveness of cervical pessary (Arabin) and vaginal progesterone for preventing premature birth in twin pregnancies after IVF

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Vietnam National University
• Collaborator: Mỹ Đức Hospital
• Treatments: Progesterone

Criteria

Inclusion Criteria:

To be eligible for enrolment into this trial, each female subject must fulfil all of the following criteria at the start of enrolment, unless specified otherwise:

• Women with a twin pregnancy (mono- and di-chorionic)

• 16 0/7 to 22 0/7 weeks of gestation

• Maternal age ≥ 18 yrs

• Cervical length less than 38 mm

• Informed consent

• Not participating in another PTB study at the same time

Exclusion Criteria:

To be eligible for enrolment in this study each subject must not meet any of the following criteria:

• History of cervical surgery

• Cervical cerclage in place

• Twin-to-twin transfusion syndrome

• Stillbirth or major congenital abnormalities in any of the fetus

• Severe vaginal discharge, acute vaginitis

• Premature rupture of membranes

• Premature labor