Central Venous Pressure Guided Hydration Prevention for Contrast-Induced Nephropathy
Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
Patients at moderate and high risk for contrast induced nephropathy (CIN) should receive
sufficient hydration before application of contrast to prevent CIN, but hydration could
obviously increase the preload for congestive heart failure (CHF) patients. It is important
to make an individual hydration protocol for patients with dysfunction of heart and renal to
reduce the incidence rate of CIN. This prospective, randomized, double-blind, comparative
clinical trial randomly selected 264 patients with estimated glomerular filtration rate,
(eGFR) <60 ml/min per 1.73 m2 and CHF undergoing coronary angiography to receive either the
convention hydration (n=132) or the central venous pressure (CVP) guided hydration (n=132).