Celecoxib in Postoperative Analgesia for Radius Fracture Surgery
Status:
Recruiting
Trial end date:
2023-09-30
Target enrollment:
Participant gender:
Summary
Patients scheduled for elective osteosynthesis of the distal radius will be randomized to
receive celecoxib 100 mg orally (PO) at 6 in the morning before surgery and every 12 hours
for 2 days thereafter, or a placebo pill in the same regimen. After surgery under general
anaesthesia, they will receive paracetamol 1 g intravenously (IV) every 6 hours and if pain
intensity is greater than 4 on a numeric rating scale (NRS) of 0-10, piritramid 15 mg
intramuscularly (IM) will be administered. Pain intensity, piritramid consumption and side
effects of treatment will be recorded in a questionnaire for 2 days.