Celecoxib as a Chemopreventive Agent in Current and Former Smokers
Status:
Completed
Trial end date:
2009-09-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is:
- To examine the effect of celecoxib treatment on Ki-67 expression, a marker of cell
proliferation, in the bronchial epithelium of current and former smokers.
- To examine the toxicity associated with celecoxib administration.
- To measure the effect of celecoxib treatment on arachidonic acid metabolites in the
bronchial epithelium of current and former smokers.