Celecoxib, Leucovorin, Fluorouracil, and Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as leucovorin, fluorouracil, and oxaliplatin, use
different ways to stop tumor cells from dividing so they stop growing or die. Celecoxib may
stop the growth of colorectal cancer by stopping blood flow to the tumor and by blocking the
enzymes necessary for tumor cell growth. Combining chemotherapy with celecoxib may kill more
tumor cells.
PURPOSE: Phase II trial to study the effectiveness of combining celecoxib with leucovorin,
fluorouracil, and oxaliplatin in treating patients who have metastatic colorectal cancer.
Phase:
Phase 2
Details
Lead Sponsor:
GERCOR - Multidisciplinary Oncology Cooperative Group Groupe Cooperateur Multidisciplinaire en Oncologie (GERCOR)