Celecoxib, Capecitabine, and Irinotecan in Treating Patients With Recurrent or Metastatic Colorectal Cancer
Status:
Completed
Trial end date:
2007-08-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Celecoxib may stop the growth of tumor cells by blocking some of the enzymes
needed for cell growth. Drugs used in chemotherapy, such as capecitabine and irinotecan, work
in different ways to stop the growth of tumor cells, either by killing the cells or by
stopping them from dividing. Giving celecoxib together with capecitabine and irinotecan may
kill more tumor cells.
PURPOSE: This phase II trial is studying how well giving celecoxib together with capecitabine
and irinotecan works in treating patients with recurrent or metastatic colorectal cancer.