Urinary tract infection (UTI) is a very common problem in young healthy women, afflicting
approximately one-half of women by their late 20s. One of the most common antibiotics used to
treat UTIs is ciprofloxacin, usually for a total of three days. However, increasing
resistance to this antibiotic has raised concerns about its overuse for cystitis and
generated interest in alternative agents. An alternative antibiotic which is approved for use
in UTIs is cefpodoxime. However, there are few studies evaluating the efficacy and tolerance
of this compound when given in a 3-day regimen as is commonly used for treatment of UTI. The
major purpose of this study is to assess the efficacy and tolerance of a 3-day regimen of
cefpodoxime versus ciprofloxacin for treatment of acute uncomplicated cystitis.