Cediranib Maleate and Combination Chemotherapy in Treating Patients With Advanced Biliary Cancers
Status:
Terminated
Trial end date:
2014-03-01
Target enrollment:
Participant gender:
Summary
This phase II trial is studying how well giving cediranib maleate together with combination
chemotherapy works in treating patients with advanced biliary cancers. Cediranib maleate may
stop the growth of tumor cells by blocking some of the enzymes needed for cell growth or by
blocking blood flow to the tumor. Drugs used in chemotherapy, such as oxaliplatin, leucovorin
calcium, and fluorouracil, work in different ways to stop the growth of tumor cells, either
by killing the cells or by stopping them from dividing. Giving cediranib maleate together
with combination chemotherapy may kill more tumor cells.