Cedar Honey in Oral Lichen Planus

• Status: Completed
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The study aimed to evaluate the effect of cedar honey in treatment of erosive and atrophic oral lichen planus ( a common oral problem).

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mashhad University of Medical Sciences

Criteria

Inclusion Criteria:

1. clinically and histopathologically confirmed oral lichen planus without dysplasia in histopathologic evaluation

2. Severity of pain≥2 (VAS score)

3. Severity of lesions≥2 (tong prasom criteria)

4. absence of any treatment in the last month

5. absence of kidney or liver diseases( due to systemic administration of fluconazole to both groups)

Exclusion Criteria:

1. evidence of lichenoid reaction in clinical or histopathologic assessment

2. loss of follow up

3. pregnant patients

4. diabetic patients

5. any other mucosal disease

6. any severe systemic disease

7. patients who refuse doctor's advice

8. any unexpected adverse effect of honey