Overview

Carotid Plaque Characteristics by MRI in AIM-HIGH (Carotid MRI Substudy)

Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
Heart attacks and strokes caused by the unstable atherosclerotic plaques remain the leading cause of death in the United States. Unstable plaques often have more fat than stable plaques. This study will investigate if a treatment with LDL-lowering plus HDL-raising compared with LDL-lowering alone would more effectively reduce the plaque fat content assessed by magnetic resonance imaging (MRI), therefore, further reducing heart attacks and strokes.
Details
Lead Sponsor:
University of Washington
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)
Treatments:
Niacin
Niacinamide
Nicotinic Acids
Simvastatin