Overview

Cardiovascular Consequences of Inhaled Short-acting Beta-agonist Use

Status:
Recruiting
Trial end date:
2024-12-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to test the impact inhalers have on blood vessels in young healthy individuals. The main question it aims to answer is if long term use of asthma inhalers have any effect on the blood vessels and heart. Participants will be asked to: - Perform lung function and exercise tests - Have ultrasound images taken of the artery in their arm - Use an inhaler for 4 weeks - Visit the lab for testing on 4-6 different occasions Researchers will compare two different inhalers (Ventolin and Symbicort) with a placebo to see if the inhalers have any effect on the blood vessels over the 4 week period.
Phase:
Phase 1
Details
Lead Sponsor:
University of Alberta
Treatments:
Albuterol
Budesonide
Formoterol Fumarate