Overview

Cardiometabolic Disease and Pulmonary Hypertension

Status:
Terminated
Trial end date:
2020-12-22
Target enrollment:
Participant gender:
Summary
This study will investigate if metformin can help people with obesity and high pressures inside their lung blood vessels. Metformin is approved by the U.S. Food and Drug Administration (FDA) to treat diabetes, but metformin is not approved by the FDA to treat pulmonary hypertension. This study will examine whether Metformin will improve the high pressure inside lung blood vessels in people who are obese. The study will help understand the effect of metformin on pressures inside lung blood vessels.
Phase:
Early Phase 1
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)
Treatments:
Metformin