Carboplatin, Gemcitabine, and Thalidomide in Patients Undergoing Surgery for Stage II or III Non-Small Cell Lung Cancer
Status:
Terminated
Trial end date:
2008-07-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as carboplatin and gemcitabine, work in different
ways to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Thalidomide may stop the growth of tumor cells by blocking blood flow to the tumor.
Giving carboplatin and gemcitabine together with thalidomide before surgery may make the
tumor smaller and reduce the amount of normal tissue that needs to be removed.
PURPOSE: This phase II trial is studying how well giving carboplatin and gemcitabine together
with thalidomide works in treating patients who are undergoing surgery for stage II or stage
III non-small cell lung cancer.