In 2009, the Society of Obstetricians and Gynecologists Canada, which produces national
clinical guidelines on important women's health issues, recommended that a bolus of
carbetocin 100 mcg into your vein should be used at elective cesarean delivery instead of
oxytocin infusion for the prevention of bleeding after you deliver your baby. Similar to
oxytocin, carbetocin has side effects that are dose-related. Although 100 mcg has been the
recommend dose, studies in nonlaboring women suggest that doses lower than 100 mcg may be
used to achieve the same degree of uterine contractility with less side effects. So far, the
ideal dose to be used in cesarean sections for labouring women who have failure to progress
in labour (failure of your cervix to dilate adequately to 10cm or the baby's head not
descending the birth canal) has not been determined. This study is designed to determine the
minimum carbetocin dose required during cesarean delivery for 'failure to progress' to
achieve the best effect.
Phase:
N/A
Details
Lead Sponsor:
Samuel Lunenfeld Research Institute, Mount Sinai Hospital