Carbetocin Versus Syntometrine for the Third Stage of Labour

• Status: Completed
• Trial end date: 2009-07-01
• Target enrollment: 0
• Participant gender: Female

Summary

Intramuscular carbetocin is as effective as intramuscular syntometrine for the prevention of postpartum haemorrhage

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National University Hospital, Singapore
• Collaborator: National Healthcare Group, Singapore
• Treatments: Carbetocin; Oxytocin; Syntometrine

Criteria

Inclusion Criteria:

1. Any pregnant woman expected to deliver vaginally

2. Age more than 21 if not married

3. Ability to provide informed consent

Exclusion Criteria:

1. Multiple pregnancy

2. Patients with other risk factors for postpartum haemorrhage

3. Patients planning to have an elective caesarean section

4. History of vascular disease such as coronary artery disease

5. History of hypertension requiring treatment within the last 2 years

6. History of hepatic or renal disease

7. Known or suspected coagulopathy

8. History of hypersensitivity to oxytocin or carbetocin

9. Any condition where the use of syntometrine/carbetocin is contraindicated