Carbetocin Versus Oxytocin in Caesarean Section for the Control of Postpartum Haemorrhage
Status:
Unknown status
Trial end date:
2015-11-01
Target enrollment:
Participant gender:
Summary
Post-partum haemorrhage is one of the life threatening emergencies. It accounts for nearly
one-quarter of all maternal death worldwide. Atonic uterus contributes about 80% among the
causes. Uterotonic drugs are administered following the delivery of baby both in vaginal and
caesarean delivery for prevention of PPH. However postpartum haemorrhage cannot always be
prevented. But, the incidence and especially its magnitude can be reduced by assessing the
risk factors and following the guidelines. The intelligent anticipation, skilled supervision,
prompt detection and effective institution of therapy can prevent a normal case from
undergoing disastrous consequences. This study will be carried out at Bangabandhu Sheikh
Mujib Medical University (BSMMU) within six months after approval. This is a Randomized
Control Trial which will compare efficacy of Carbetocin and Oxytocin for the control of PPH.
Structured Questionnaire, Data Sheet, hospital indoor documents i.e. Patient chart, operation
notes, surgeons visual estimation of blood loss etc will be used as study tool. Ethical
clearance will be obtained from Institutional Review Board of BSMMU. Written informed consent
will be obtained from the patient or from her legal guardian. Patient confidentiality will be
strictly maintained. No name, address or contact details of the patient will be divulged.
Phase:
Early Phase 1
Details
Lead Sponsor:
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh