Overview

CarbacholĀ“s Headache Inducing Characteristics and Effects on the Cerebral Blood Flow

Status:
Completed
Trial end date:
2007-04-01
Target enrollment:
0
Participant gender:
All
Summary
To investigate headache score and accompanying symptoms during and after infusion of carbachol.
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Danish Headache Center
Treatments:
Carbachol
Criteria
Inclusion Criteria:

- Healthy volunteers

- Aged 18-40

- 50-100 kg

- Fertile women must use safe contraceptives (IUD, oral contraceptives, surgical
sterilisation and long lasting gestagen.

Exclusion Criteria:

- Tension type headache more than once/month

- Other primary headaches

- Daily medication except contraceptives

- Drug taken within 4 times the halflife for the specific drug except contraceptives

- Pregnant or lactating women

- Exposure to radiation within the last year

- Headache within the last 24 hours before start of trial

- Hypertension

- Hypotension

- Respiratory or cardiac disease