Cannabis Oil for Chronic Non-Cancer Pain Treatment
Status:
Unknown status
Trial end date:
2021-01-30
Target enrollment:
Participant gender:
Summary
Cannabis is being prescribed medically for chronic non-cancer pain despite limited evidence
whether or not it works to reduce average pain in patients with chronic non-cancer pain. The
cannabis plant (Cannabis sativa, Cannabis indica) consists of several hundred compounds of
which, approximately 70 of which are thought to be active. The two active cannabinoids of
interest in this trial are tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD). The goal of
this trial is to determine whether CBD or CBD+THC reduces the average pain in participants
with chronic non-cancer pain. The investigators also aim to determine whether CBD or CBD+THC
is associated with a reduction in pain severity, pain interference, anxiety, depression,
insomnia, opioids and use of benzodiazepines, analgesics, antidepressants, anxiolytics, or
hypnotics amongst chronic non-cancer pain patients or an increase in physical functioning,
physical health related role limitations, social functioning, mental functioning.
Phase:
Phase 2
Details
Lead Sponsor:
Hamilton Health Sciences Corporation
Collaborator:
Michael G. DeGroote Institute for Pain Research and Care, McMaster University